Staff

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Dr. YU Chak Yan, Marco 余澤仁博士
Dr YU Chak Yan, Marco （余澤仁博士）
BSS (HKU)
PhD (CUHK)

Assistant Professor

Tel : (852) 3963 5245

Dr Yu received his BSS in Social Science Statistics and Risk Management from The University of Hong Kong, and obtained his PhD degree from The Chinese University of Hong Kong. His research Interests include functional data analysis, medical signal/image processing and analysis, and financial time series analysis.


Research InterestsService and Professional ExperiencePublicationsResearch Grants
TopResearch Interests
  • Functional data analysis
  • Medical signal/image processing and analysis
  • Financial time series analysis
TopService and Professional Experience
  1. Honorary Postgraduate Fellow, Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong
TopPublications

..........Journal Articles..........

  1. Chan, T. C. Y., Wang, Y., Ng, A. L. K., Zhang, J., Yu, M. C. Y., Jhanji, V., & Cheng, G. P. M. (2018). Vector analysis of high (≥3 diopters) astigmatism correction using small-incision lenticule extraction and laser in situ keratomileusis. Journal of Cataract and Refractive Surgery. https://doi.org/10.1016/j.jcrs.2018.04.038
  2. Wan, K. H., Chan, T. C., Yu, M., & Jhanji, V. (2018). Longitudinal evaluation of posterior corneal changes after laser in situ keratomileusis in high myopia: a swept-source optical coherence tomography study. Clinical & Experimental Ophthalmology. https://doi.org/10.1111/ceo.13178
  3. Chan, T. C., Wang, Y. M., Yu, M., & Jhanji, V. (2017). Comparison of corneal dynamic parameters and tomographic measurements using Scheimpflug imaging in keratoconus. The British Journal of Ophthalmology. https://doi.org/10.1136/bjophthalmol-2017-310355
  4. Chan, T. C. Y., Wong, E. S., Chan, J. C. K., Wang, Y., Yu, M., Maeda, N., & Jhanji, V. (2017). Corneal backward scattering and higher-order aberrations in children with vernal keratoconjunctivitis and normal topography. Acta Ophthalmologica. https://doi.org/10.1111/aos.13566
  5. Chan, T. C. Y., Yu, M. C. Y., Mak, S., & Jhanji, V. (2017). Longitudinal comparison of femtosecond-assisted sub-Bowman keratomileusis versus photorefractive keratectomy for high myopia. The British Journal of Ophthalmology, 101(3), 275–282. https://doi.org/10.1136/bjophthalmol-2016-308642
  6. Jhanji, V., Chan, T. C. Y., Li, W. Y., Lim, R. R., Yu, M. C. Y., Law, K., … Mohan, R. R. (2017). Conventional Versus Inverted Side-cut Flaps for Femtosecond Laser-Assisted LASIK: Laboratory and Clinical Evaluation. Journal of Refractive Surgery (Thorofare, N.J.: 1995), 33(2), 96–103. https://doi.org/10.3928/1081597X-20161102-02
  7. Lin, C., Mak, H., Yu, M., & Leung, C. K.-S. (2017). Trend-Based Progression Analysis for Examination of the Topography of Rates of Retinal Nerve Fiber Layer Thinning in Glaucoma. JAMA Ophthalmology, 135(3), 189–195. https://doi.org/10.1001/jamaophthalmol.2016.5111
  8. Tan, S., Yu, M., Baig, N., Hansapinyo, L., & Tham, C. C. (2017). Agreement of patient-measured intraocular pressure using rebound tonometry with Goldmann applanation tonometry (GAT) in glaucoma patients. Scientific Reports, 7, 42067. https://doi.org/10.1038/srep42067
  9. Teng, Y., Yu, M., Wang, Y., Liu, X., You, Q., & Liu, W. (2017). OCT angiography quantifying choriocapillary circulation in idiopathic macular hole before and after surgery. Graefe’s Archive for Clinical and Experimental Ophthalmology. https://doi.org/10.1007/s00417-017-3586-0
  10. 10. Wang, Y. M., Chan, T. C., Yu, M. C. Y., & Jhanji, V. (2017). Comparative evaluation of progression rate in keratoconus before and after collagen crosslinking. The British Journal of Ophthalmology. https://doi.org/10.1136/bjophthalmol-2017-311017
  11. Wang, Y. M., Chan, T. C. Y., Yu, M., & Jhanji, V. (2017). Comparison of Corneal Dynamic and Tomographic Analysis in Normal, Forme Fruste Keratoconic, and Keratoconic Eyes. Journal of Refractive Surgery (Thorofare, N.J.: 1995), 33(9), 632–638. https://doi.org/10.3928/1081597X-20170621-09
  12. Wang, Y. M., Chan, T. C. Y., Yu, M., & Jhanji, V. (2017). Shift in progression rate of keratoconus before and after epithelium-off accelerated corneal collagen crosslinking. Journal of Cataract and Refractive Surgery, 43(7), 929–936. https://doi.org/10.1016/j.jcrs.2017.04.033
  13. Wu, Z., Lin, C., Crowther, M., Mak, H., Yu, M., & Leung, C. K.-S. (2017). Impact of Rates of Change of Lamina Cribrosa and Optic Nerve Head Surface Depths on Visual Field Progression in Glaucoma. Investigative Ophthalmology & Visual Science, 58(3), 1825–1833. https://doi.org/10.1167/iovs.16-20509
  14. Chan, T. C. Y., Biswas, S., Yu, M., & Jhanji, V. (2016). Comparison of corneal measurements in keratoconus using swept-source optical coherence tomography and combined Placido-Scheimpflug imaging. Acta Ophthalmologica. https://doi.org/10.1111/aos.13298
  15. Chan, T. C. Y., Yu, M. C. Y., Mak, S., & Jhanji, V. (2016). Longitudinal comparison of femtosecond-assisted sub-Bowman keratomileusis versus photorefractive keratectomy for high myopia. The British Journal of Ophthalmology. http://doi.org/10.1136/bjophthalmol-2016-308642
  16. Chan, T. C. Y., Yu, M. C. Y., Ng, A. L. K., Cheng, G. P. M., Zhang, J., Wang, Y., & Jhanji, V. (2016). Short-term Variance of Refractive Outcomes After Simultaneous LASIK and High-Fluence Cross-linking in High Myopic Correction. Journal of Refractive Surgery, 32(10), 664–670. https://doi.org/10.3928/1081597X-20160728-01
  17. Chan, T. C. Y., Yu, M. C. Y., Ng, A., Wang, Z., Cheng, G. P. M., & Jhanji, V. (2016). Early outcomes after small incision lenticule extraction and photorefractive keratectomy for correction of high myopia. Scientific Reports, 6, 32820. http://doi.org/10.1038/srep32820
  18. Chen, S., Chan, T. C. Y., Zhang, J., Ding, P., Chan, J. C. K., Yu, M. C. Y., Li, Y., Jhanji, V., & Wang, Q. (2016). Epithelium-on corneal collagen crosslinking for management of advanced keratoconus. Journal of Cataract and Refractive Surgery, 42(5), 738–749. http://doi.org/10.1016/j.jcrs.2016.02.041
  19. Kam, K. W., Leung, K. S., Kwok, R. P. W., Yu, M., Li, F. C. H., Young, A. L., & Jhanji, V. (2016). Clinical features, diagnosis and treatment outcomes of cytomegalovirus endotheliitis in Hong Kong. Acta Ophthalmologica. http://doi.org/10.1111/aos.13109
  20. Ye, C., Yu, M., & Leung, C. K.-S. (2016). Impact of segmentation errors and retinal blood vessels on retinal nerve fibre layer measurements using spectral-domain optical coherence tomography. Acta Ophthalmologica, 94(3), e211–219. http://doi.org/10.1111/aos.12762
  21. Yu, M., Lin, C., Weinreb, R. N., Lai, G., Chiu, V., & Leung, C. K.-S. (2016). Risk of Visual Field Progression in Glaucoma Patients with Progressive Retinal Nerve Fiber Layer Thinning: A 5-Year Prospective Study. Ophthalmology, 123(6), 1201–1210. http://doi.org/10.1016/j.ophtha.2016.02.017
  22. Chan, T. C. Y., Biswas, S., Yu, M., & Jhanji, V. (2015). Longitudinal Evaluation of Cornea With Swept-Source Optical Coherence Tomography and Scheimpflug Imaging Before and After Lasik. Medicine, 94(30), e1219. http://doi.org/10.1097/MD.0000000000001219
  23. Chan, T. C. Y., Liu, D., Yu, M., & Jhanji, V. (2015). Longitudinal evaluation of posterior corneal elevation after laser refractive surgery using swept-source optical coherence tomography. Ophthalmology, 122(4), 687–692. http://doi.org/10.1016/j.ophtha.2014.10.011
  24. Chow, V. W. S., Chan, T. C. Y., Yu, M., Wong, V. W. Y., & Jhanji, V. (2015). One-year outcomes of conventional and accelerated collagen crosslinking in progressive keratoconus. Scientific Reports, 5, 14425. http://doi.org/10.1038/srep14425
  25. Fong, Y. Y. Y., Yu, M., Young, A. L., & Jhanji, V. (2015). Presentation and Management Outcomes of Corneal and Scleral Perforations in Geriatric Nursing Home Residents. Medicine, 94(36), e1518–0. http://doi.org/10.1097/MD.0000000000001518
  26. Tan, S., Yu, M., Baig, N., Chan, P. P.-M., Tang, F. Y., & Tham, C. C. (2015). Circadian Intraocular Pressure Fluctuation and Disease Progression in Primary Angle Closure Glaucoma. Investigative Ophthalmology & Visual Science, 56(8), 4994–5005. http://doi.org/10.1167/iovs.15-17245
  27. Wong, R. C. Y., Yu, M., Chan, T. C. Y., Chong, K. K. L., & Jhanji, V. (2015). Longitudinal comparison of outcomes after sub-Bowman keratomileusis and laser in situ keratomileusis: randomized, double-masked study. American Journal of Ophthalmology, 159(5), 835–845.e3. http://doi.org/10.1016/j.ajo.2015.02.003
  28. Wu, Z., Xu, G., Weinreb, R. N., Yu, M., & Leung, C. K. S. (2015). Optic Nerve Head Deformation in Glaucoma: A Prospective Analysis of Optic Nerve Head Surface and Lamina Cribrosa Surface Displacement. Ophthalmology, 122(7), 1317–1329. http://doi.org/10.1016/j.ophtha.2015.02.035
  29. Ye, C., Yu, M., & Jhanji, V. (2015). Stromal bed thickness measurement during laser in situ keratomileusis using intraoperative optical coherence tomography. Cornea, 34(4), 387–391. http://doi.org/10.1097/ICO.0000000000000345
  30. Ye, C., Yu, M., Lai, G., & Jhanji, V. (2015). Variability of Corneal Deformation Response in Normal and Keratoconic Eyes. Optometry and Vision Science: Official Publication of the American Academy of Optometry, 92(7), e149–153. http://doi.org/10.1097/OPX.0000000000000628
  31. Liu, S., Yu, M., Weinreb, R. N., Lai, G., Lam, D. S.-C., & Leung, C. K.-S. (2014) A Prospective Study of Frequency Doubling Technology Perimetry for Detection of Glaucoma Progression – A Linear Pointwise Regression Analysis. Investigative ophthalmology & visual science, 55(5), 2862-2869. doi:10.1167/iovs.13-13225
  32. Liu, S., Yu, M., Weinreb, R. N., Lai, G., Lam, D. S.-C., & Leung, C. K.-S. (2014). Frequency-Doubling Technology Perimetry for Detection of the Development of Visual Field Defects in Glaucoma Suspect Eyes: A Prospective Study. JAMA ophthalmology, 132(1), 77-83. doi:10.1001/jamaophthalmol.2013.5511
  33. Yip, Y. W., Yu, M., &Jhanji, V. (2014) Randomized, contralateral eye study to evaluate the effect of standard and inverted side-cut angle on corneal biomechanical properties during femtosecond laser-assisted in situ keratomileusis. ActaOphthalmologica, 92(6), e437-442. doi: 10.1111/aos.12396
  34. Choi, O. T. K., Wong, H., Yiu, C. K. F., &Yu, M. (2013). In Depth Analysis of the Dually Listed Companies in Hong Kong and China Stock Markets Prior and Posterior to the Global Financial Turmoil. International Journal of Economics and Finance, 5(10). doi:10.5539/ijef.v5n10p100
  35. Chow, V. W. S., Biswas, S., Yu, M., Wong, V. W. Y., &Jhanji, V. (2013). Intraoperative Pachymetry Using Spectral-Domain Optical Coherence Tomography during Accelerated Corneal Collagen Crosslinking. BioMed Research International, 2013, 1–6. doi:10.1155/2013/848363
  36. Jhanji, V., Yang, B., Yu, M., Ye, C., & Leung, C. K. (2013). Corneal thickness and elevation measurements using swept source optical coherence tomography and slit scanning topography in normal and keratoconic eyes. Clinical & experimental ophthalmology, 41(8), 735-745. doi:10.1111/ceo.12113
  37. Lai, I., Mak, H., Lai, G., Yu, M., Lam, D. S. C., & Leung, C. K. S. (2013). Anterior Chamber Angle Imaging with Swept-Source Optical Coherence Tomography: Measuring Peripheral Anterior Synechia in Glaucoma. Ophthalmology, 120(6), 1144-1149. doi:10.1016/j.ophtha.2012.12.006
  38. Leung, C. K. S., Ye, C., Weinreb, R. N., Yu, M., Lai, G., & Lam, D. S. (2013). Impact of Age-related Change of Retinal Nerve Fiber Layer and Macular Thicknesses on Evaluation of Glaucoma Progression. Ophthalmology, 120(12), 2485-2492.doi:10.1016/j.ophtha.2013.07.021
  39. McKee, H., Ye, C., Yu, M., Liu, S., Lam, D. S. C., & Leung, C. K. S. (2013). Anterior Chamber Angle Imaging With Swept-Source Optical Coherence Tomography: Detecting the Scleral Spur, Schwalbe’s Line, and Schlemm’s Canal. Journal of glaucoma, 22(6), 468-472. doi:10.1097/IJG.0b013e31824485fa
  40. Agarwal, T., Bhartiya, S., Dada, T., Panda, A., Jhanji, V., &Yu, M. (2012). Agreement of corneal thickness measurement using slitlamp and ultrasound pachymetry. Eye & contact lens, 38(4), 231–233. doi:10.1097/ICL.0b013e318250884e
  41. Leung, C. K.-S., Yu, M., Weinreb, R. N., Lai, G., Xu, G., & Lam, D. S.-C. (2012). Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: patterns of retinal nerve fiber layer progression. Ophthalmology, 119(9), 1858–1866. doi:10.1016/j.ophtha.2012.03.044
  42. Leung, C. K.-S., Yu, M., Weinreb, R. N., Mak, H. K., Lai, G., Ye, C., & Lam, D. S.-C. (2012). Retinal Nerve Fiber Layer Imaging with Spectral-Domain Optical Coherence Tomography: Interpreting the RNFL Maps in Healthy Myopic Eyes. Investigative ophthalmology & visual science, 53(11), 7194–7200. doi:10.1167/iovs.12-9726
  43. Leung, C. K. S., Yu, M., Weinreb, R. N., Ye, C., Liu, S., Lai, G., & Lam, D. S. C. (2012). Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a prospective analysis of age-related loss. Ophthalmology, 119(4), 731–737. doi:10.1016/j.ophtha.2011.10.010
  44. Yang, B., Ye, C., Yu, M., Liu, S., Lam, D. S. C., & Leung, C. K. (2012). Optic disc imaging with spectral-domain optical coherence tomography: variability and agreement study with Heidelberg retinal tomograph. Ophthalmology, 119(9), 1852–1857. doi:10.1016/j.ophtha.2012.02.033
  45. Leung, C. K.-S., Chiu, V., Weinreb, R. N., Liu, S., Ye, C., Yu, M., Cheung, C. Y.-L., et al. (2011). Evaluation of retinal nerve fiber layer progression in glaucoma: a comparison between spectral-domain and time-domain optical coherence tomography. Ophthalmology, 118(8), 1558–1562. doi:10.1016/j.ophtha.2011.01.026
  46. Li, Z., Liu, S., Weinreb, R. N., Lindsey, J. D., Yu, M., Liu, L., Ye, C., et al. (2011). Tracking dendritic shrinkage of retinal ganglion cells after acute elevation of intraocular pressure. Investigative ophthalmology & visual science, 52(10), 7205–7212. doi:10.1167/iovs.10-6868
  47. Liu, S., Yu, M., Ye, C., Lam, D. S. C., & Leung, C. K.-S. (2011). Anterior chamber angle imaging with swept-source optical coherence tomography: an investigation on variability of angle measurement. Investigative ophthalmology & visual science, 52(12), 8598–8603. doi:10.1167/iovs.11-7507
  48. Ye, C., To, E., Weinreb, R. N., Yu, M., Liu, S., Lam, D. S. C., & Leung, C. K. S. (2011). Comparison of retinal nerve fiber layer imaging by spectral domain optical coherence tomography and scanning laser ophthalmoscopy. Ophthalmology, 118(11), 2196–2202. doi:10.1016/j.ophtha.2011.03.035
  49. Yu, M., Weinreb, R. N., Yiu, C., Liu, S., Or, M. K., Ye, C., Lam, D. S.-C., et al. (2011). Computer simulation of progressive retinal nerve fiber layer loss in glaucoma: performance of event and trend analyses. Investigative ophthalmology & visual science, 52(13), 9674–9683. doi:10.1167/iovs.11-8052
 

..........Conference Proceedings & Book Chapters..........

  1. Yu, M., & Tang, R. (2018, July). Prediction of Retinal Nerve Fiber Layer Thickness Maps in Glaucoma Using Spatio-temporal Model. Presented at the 3rd Asia Pacific Tele-Ophthalmology Society (APTOS) Symposium, Outram, Singapore.
 

..........Technical Reports..........

  1. Leung C. K., Yu, M., Lam D. S. (2013). “Detection of Disease-related Retinal Nerve Fiber Layer Thinning,” U.S. Patent Application No. 13/898,176 , Publication No. US20130308824 A1. Washington, DC: U.S.
TopResearch Grants
  1. (UGC/FDS14/M01/15) HK$ 1,059,083. “Investigation of Spatio-temporal Relationship between the Structure and Function in Glaucoma Using Partial Least Squares Regression (PLS-R),” funded by the University Grants Committee (UGC) 2015/2016
  2. (UGC/IIDS14/P01/14) HK$381,570.“Workshop Series in Applied Statistics,” funded by the University Grants Committee (UGC) 2014/2015
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